| Field | Specification |
|---|---|
| Mfr No | |
| Alternative Names | USP6 N-terminal-like protein; Related to the N-terminus of tre; RN-tre; USP6NL; KIAA0019 |
| Conjugate | |
| Formulation | |
| Host | |
| Immunogen | Synthetic peptide, corresponding to amino acids 446-491 of Human USP6NL. |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Reactivity | |
| Storage |
Product Overview
Research Use OnlyGTPase-activating proteins(GAPs) accelerate the intrinsicrate of GTP hydroysis of Ras-related proteins, resulting in downregulation of their active form.RN-tre (related to the N-terminus of tre), also known as USP6NL(USP6 Nterminal like) or TRE2NL, is an 828 amino acid protein thatcontains one RabGAP TBC domain. Expressed in awide variety of tissues, RN-tre functions as a GTPase-activating protein for Rab 5A and isthought to be involved in receptor trafficking, aswell asin the inhibition of EGFR internalization. In response to DNA damage, RN-tre may be phosphorylated by ATM or ATR.
Validated Applications
| Western Blot (WB) | 1:500~1:1000 |
|---|
Key Specifications
| Host Species | Rabbit |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Conjugate | Unconjugated |
| Purification | Affinity Purification |
| Formulation | Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
| Molecular Weight | ~ 86 kDa |
| Catalog No. | BS61476 |
| UniProt | Q92738 |
| Alternative Names | USP6 N-terminal-like protein; Related to the N-terminus of tre; RN-tre; USP6NL; KIAA0019 |
Immunogen / Antigen
Synthetic peptide, corresponding to amino acids 446-491 of Human USP6NL.
Reactivity Notes
USP6NL polyclonal antibody detects endogenous levels of USP6NL protein.
Storage & Handling
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Safety
For Research Use Only (RUO). Not intended for diagnostic, therapeutic, or veterinary use. Handle according to standard laboratory biosafety guidelines. Avoid skin and eye contact. Dispose of waste in accordance with local regulations.
This antibody has been validated for: Western Blot. For each application, follow the recommended dilutions on the product datasheet and optimize empirically for your sample type.
WB: 1:500~1:1000
This antibody has been confirmed reactive against: Human, Mouse, Rat. Cross-reactivity with other species may occur due to sequence homology but is not guaranteed without independent validation.
Synthetic peptide, corresponding to amino acids 446-491 of Human USP6NL.
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Avoid repeated freeze-thaw cycles. Centrifuge vials briefly before opening. Dilute immediately before use.
Customization & Add-ons: Can't find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.
