| Field | Specification |
|---|---|
| Alternative names | (3R,6R,9S,12S,15R,18R,21S,24S,27R,30R,33S,36S)-3,6,9,15,18,21,27,30,33-Nonaisopropyl-12,24,36-trimethyl-1,7,13,19,25,31-hexaoxa-4,10,16,22,28,34-hexaazacyclohexatriacontane-2,5,8,11,14,17,20,23,26,29, 32,35-dodecone |
| CAS no. | |
| Applications | |
| Source | Synthetic |
| Molecular weight | |
| Molecular formula | C54H90N6O18 |
| Purity | |
| Bioactivity | Inducer |
| Activity | |
| Solubility | Soluble to 25 mM in DMSO and 25 mM in ethanol. |
| SMILES | |
| InChIKey | |
| Form | White Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Valinomycin is a potassium-selective ionophore that facilitates the transport of K+ ions across lipid membranes. It is used in neuroscience to study membrane potential, ion homeostasis, and mitochondrial function. Valinomycin-induced changes in potassium gradients can influence neuronal excitability and apoptosis, making it a useful tool in neurodegenerative disease models.
Classification: Very Toxic. May be fatal if inhaled, swallowed or absorbed through skin.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
- S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
Risk Phrases:
- R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
- R68 - Possible risk of irreversible effects
Hazard Phrases:
H300-H310
Precautionary Phrases:
P264-P280-P302 + P350-P310
Valinomycin (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-230)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
2. Cammann K. (1985) Top Curr Chem. 128: 219-258.
