Vandetanib

SKU:BHB11900266
Suppliers
StressMarq Biosciences Inc.
StressMarq Biosciences Inc.
Details Products
Overview
Click light‑blue chips for details
Vandetanib is a research-grade small-molecule inhibitor of VEGFR supporting Cell Signaling and Cancer research. Supplied as a yellow solid with 98% purity (CAS 443913-73-3, MW 475.4) soluble in DMSO or EtOH; store at -20°C. For research use only.
Cas No. 443913-73-3
Molecular Formula C22H24BrFN4O2
Purity ≥98% (HPLC)
Application Notes VEGFR inhibitor
Options selector
Catalog no. Size
SIH-483-10MG 10 mg
SIH-483-50MG 50 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size (2) — 10 mg, 50 mg.
  • Lead time: options listed as “in stock at manufacturer” typically ship in 2-3 business days; other statuses may take longer.
  • Storage: -20ºC
  • Shipping: ships at ambient temperature.
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No SIH-483
Activity
  • Inhibitor
Alternative Names N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine
Cas No. 443913-73-3
Form Yellow solid
Molecular Weight 475.4
Product Type
  • Biochemicals
  • Small Molecules
Purity ≥98% (HPLC)
Shipping Shipped Ambient
SMILES C1=C3C(=CC(=C1OC)OCC2CCN(CC2)C)N=CN=C3NC4=CC=C(Br)C=C4F
Solubility Soluble in DMSO (30 mg/ml) or EtOH (10 mg/ml)
Source Synthetic
Storage -20ºC

Vandetanib is a selective inhibitor of VEGFR2 (Flk-1) and VEGFR3 (Flt-4), both of which are involved in angiogenesis and lymphangiogenesis. In neurodegenerative disease research, Vandetanib is used to study the role of VEGF signaling in neurovascular integrity, inflammation, and neuronal survival. Its ability to modulate vascular permeability and glial responses makes it a valuable compound for investigating vascular contributions to neurodegeneration and CNS repair.

Classification: Not a hazardous substance or mixture.

Safety Phrases:

  • S22 - Do not breathe dust.
  • S24/25 - Avoid contact with skin and eyes.
  • S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.

Vandetanib (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-483)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

1. Bruns C.J., et al. (2000) Clin. Cancer. Res: J. Am. Assoc. Cancer Res. 6(5): 1936–1948.

Get a Quote

Please use this form for bulk quantity requests or customized products.

Contact Information

Product Information

Try Celltrypse Free – Request Your Sample Today

Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

Try Celltrypse Free – Request Your Sample Today

Try Celltrypse Free – Request Your Sample Today

Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

Try Celltrypse Free – Request Your Sample Today