| Field | Specification |
|---|---|
| Alternative names | 2-(3,4-Dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-isopropylpentanenitrile hydrochloride (1:1) |
| CAS no. | |
| Applications | |
| Source | Synthetic |
| Molecular weight | |
| Molecular formula | C27H38N2O4•HCl |
| Purity | |
| Bioactivity | Inhibitor |
| Activity | |
| Solubility | Soluble to 100 mM in ethanol and to 50 mM in water |
| SMILES | |
| InChIKey | |
| Form | White Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Verapamil HCl is a phenylalkylamine-class L-type calcium channel blocker widely used in cardiovascular medicine. In neuroscience, its ability to inhibit voltage-dependent calcium channels has made it a valuable tool for studying calcium signaling in neurons. Verapamil has been investigated for its neuroprotective effects, particularly in models of excitotoxicity and neurodegeneration where calcium dysregulation plays a central role. Its modulation of intracellular calcium levels may influence synaptic transmission, neuronal excitability, and apoptotic pathways, making it relevant in research on stroke, epilepsy, and neurodegenerative diseases.
Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin.
Safety Phrases:
- S22 - Do not breathe dust
- S24/25 - Avoid contact with skin and eyes
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
- S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)
Risk Phrases:
- R23/24/25 - Toxic by inhilation, in contact with skin and if swallowed
- R60 - May impair fertility
- R61 - May cause harm to the unborn child
- R68 - Possible risk of irreversible effects
Hazard Phrases:
H301-H311-H331
Precautionary Phrases:
P261-P280-P301 + P310-P311
Verapamil HCl (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-308)
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