Veratridine

SKU:BHB11900089
Suppliers
StressMarq Biosciences Inc.
StressMarq Biosciences Inc.
Details Products
Overview
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Veratridine is a research-grade small-molecule activator of Na channel supporting Neuroscience and Ion Channels research. Supplied as a white solid with >98% purity (CAS 71-62-5, MW 673.79) soluble in DMSO or 100% ethanol; store at -20°C. For research use only.
Cas No. 71-62-5
Molecular Formula C36H51NO11
Purity >98%
Application Notes Na channel activator
Options selector
Catalog no. Size
SIH-300-10MG 10 mg
SIH-300-50MG 50 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size (2) — 10 mg, 50 mg.
  • Lead time: options listed as “in stock at manufacturer” typically ship in 2-3 business days; other statuses may take longer.
  • Storage: -20ºC
  • Shipping: ships at ambient temperature.
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No SIH-300
Activity
  • Activator
Alternative Names (3β,4α,16β)-4,12,14,16,17,20-Hexahydroxy-4,9-epoxycevan-3-yl 3,4-dimethoxybenzoate
Cas No. 71-62-5
Form White solid
Molecular Weight 673.79
Product Type
  • Biochemicals
  • Small Molecules
Purity >98%
Shipping Shipped Ambient
SMILES C[C@H]1CC[C@H]2[C@@]([C@]3([C@H](C[C@]4([C@@H]5CC[C@H]6[C@]7([C@]5(C[C@]4([C@@H]3CN2C1)O)O[C@@]6([C@H](CC7)OC(=O)C8=CC(=C(C=C8)OC)OC)O)C)O)O)O)(C)O
Solubility Soluble in DMSO (25 mg/ml) or 100% ethanol (25 mg/ml)
Source Synthetic
Storage -20ºC

Veratridine is a steroid-derived alkaloid that functions as a neurotoxin by persistently activating voltage-gated sodium channels. It binds to intramembrane receptor site 2, leading to prolonged sodium influx and increased intracellular calcium levels. This compound is commonly used in neuroscience to model excitotoxicity and investigate calcium-dependent signaling pathways, neuronal excitability, and neurodegenerative processes.

Classification: Caution: Substance not yet fully tested.

Safety Phrases:

  • S22 - Do not breathe dust
  • S24/25 - Avoid contact with skin and eyes
  • S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Hazard Phrases:

H302-H315-H317-H318-H335

Precautionary Phrases:

P261-P280-P305 + P351 + P338

Veratridine (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-300)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

1. Sperelakis N., Pappano A.J. (1969) J Gen Physiol. 53(1): 97-114.

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