| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | Vincaleukoblastine |
| Cas No. | |
| Form | White powder. |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in DMSO, methanol or water (25 mg/ml). |
| Source | Synthetic |
| Storage |
Vinblastine sulfate is a microtubule-disrupting agent that binds to tubulin and inhibits microtubule polymerization. In neuroscience, it is used to study axonal transport, mitotic arrest, and neuronal morphology. Microtubule dynamics are essential for neuronal function, and their disruption is implicated in neurodegenerative diseases such as Alzheimer’s and ALS. Vinblastine serves as a tool to investigate cytoskeletal integrity, intracellular trafficking, and neurotoxicity mechanisms.
Classification: D1B- Toxic Material Causing Immediate and Serious Toxic Effects, Toxic by ingestion, D2B- Toxic Material Causing Other Toxic Effects, Moderate skin irritant, Moderate eye irritant, Mutagen
Safety Phrases:
- S22 - Do not breathe dust.
- S24/25 - Avoid contact with skin and eyes.
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Hazard statements:
- H302- Harmful if swallowed.
- H315- Causes skin irritation.
- H318- Causes serious eye damage.
- H335- May cause respiratory irritation.
Precautionary statements:
- P261- Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
- P280- Wear protective gloves/ eye protection/ face protection.
- P305 + P351 + P338- IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Vinblastine sulfate (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-407)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
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Send the CAS or structure and your specs. We can help source it, suggest close
equivalents, or discuss custom synthesis with the right QC documentation (RUO).
2. Adiseshaiah P.P., et al. (2013) Cancer Lett. 337(2): 254-65.
