| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Cas No. | |
| Concentration | |
| Form | Lyophilized Powder |
| Product Type | |
| Purity | |
| Reconstitution | |
| Shipping | |
| Solubility | Up to 100mM in DMSO. Centrifuge all products before use (10000 x g 5 min). |
| Source | Synthetic |
| Storage | |
| Target |
Product details
- Chemical name: N-ethyl-5-methyl-2-propan-2-ylcyclohexane-1-carboxamide.
- Also known as: N-Ethyl-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide, Ethyl menthane carboxamide, N-Ethyl-p-menthane-3-carboxamide, N-Ethyl-2-isopropyl-5-methylcyclohexanecarboxamide
- CAS number: 39711-79-0
- Molecular formula: C13H25NO.
- Purity: >98%
- Concentration: 0.1-10 µM.
- Form: Lyophilized Powder
- Solubility: Up to 100mM in DMSO. Centrifuge all products before use (10000 x g 5 min).
- Reconstitution: Up to 100mM in DMSO. Centrifuge all products before use (10000 x g 5 min).
- Shipping: Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
- Target: TRPM8 channel
- Source: Synthetic
- Activity: WS 3 is a TRPM8 channel activator (EC50 = 3.7 μM)1.
- Alternative names: N-Ethyl-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide, Ethyl menthane carboxamide, N-Ethyl-p-menthane-3-carboxamide, N-Ethyl-2-isopropyl-5-methylcyclohexanecarboxamide
Scientific background
WS 3 is a synthetic, selective TRPM8 channel agonist with an EC50 value of 3.7 μM1,3.TRPM8 is a Ca2+-permeable channel, a member of the 'long' or melastatin (M) group of TRP proteins and is activated by temperatures or by cooling compounds such as icilin, menthol and eucalyptol. The TRPM8 gene is expressed and is up-regulated in prostate cancer and other malignancies. It is specifically expressed in temperature-sensing trigeminal and dorsal root ganglion neurons1-3.
Lead time: 1-2 Business Days
Country of origin: Israel/IL
Applications key
Application key: FC- Flow cytometry, IFC- Indirect flow cytometry, IHC- Immunohistochemistry,LCI- Live cell imaging, Calcium imaging assay,Cell survival assay, Electrophysiology, Neurite outgrowth assay.
Bioassay tested: Yes
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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