| Field | Specification |
|---|---|
| Alternative names | RO7445482 sodium |
| CAS no. | |
| Applications | |
| Molecular weight | |
| Molecular formula | C664H814F17N231Na57O415P57S6 |
| Purity | |
| Form | Solid |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Xalnesiran sodium, also known as RO7445482 sodium, is a small interfering RNA molecule that targets a conserved region of the hepatitis B virus (HBV) genome. It can be used for research into chronic hepatitis B infection[1][2][3]. It is supplied as a white to off-white solid (C664H814F17N231Na57O415P57S6, MW 21009.2 as the free acid) at 95.90% purity.
Physical & Chemical Properties
| CAS Number | 2538784-49-3 |
|---|---|
| Molecular Formula | C664H814F17N231Na57O415P57S6 |
| Molecular Weight | 21009.2 (free acid) g/mol |
| Purity | 95.90% |
| Appearance | Solid |
| Color | White to off-white |
| Signaling Pathway | Anti-infection |
| Storage | -20°C, sealed storage, away from moisture. In solvent: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with the Safety Data Sheet and your institution's chemical hygiene plan.
In Vitro
Xalnesiran sodium silences multiple HBV transcripts through post-transcriptional gene silencing and suppresses production of hepatitis B surface antigen[1].
Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.
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