| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Source | Plant — Compositae Ondetia linearis Benth.; Plant — Umbelliferae |
| Molecular weight | |
| Molecular formula | C26H30O4 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Xanthoangelol F is a prenylated (geranylated) chalcone with antibacterial activity that can be isolated from Angelica keiskei. It inhibits growth of the Gram-positive bacteria Bacillus subtilis, Staphylococcus epidermidis, and Micrococcus luteus, with an MIC of 64 μg/mL[1][2]. It has the molecular formula C26H30O4 and a molecular weight of 406.52 g/mol.
Physical & Chemical Properties
| CAS Number | 265652-71-9 |
|---|---|
| Molecular Formula | C26H30O4 |
| Molecular Weight | 406.52 g/mol |
| Structure Classification | Flavonoids Chalcones Phenols Polyphenols |
| SMILES | C(/C=C(/CCC=C(C)C)\C)C1=C(OC)C=CC(C(/C=C/C2=CC=C(O)C=C2)=O)=C1O |
| Signaling Pathway | Anti-infection |
| Initial Source | Plant — Compositae Ondetia linearis Benth.; Plant — Umbelliferae |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
[2]. Sugamoto K, et al. Synthesis and antibacterial activity of chalcones bearing prenyl or geranyl groups from Angelica keiskei[J]. Tetrahedron, 2011, 67(29): 5346-5359.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
In Vitro
In the Staphylococcus aureus USA300-Phlam-GFP strain, Xanthoangelol F (20 μM) does not inhibit the SaeRS two-component system[1]. Xanthoangelol F (1-256 μg/mL; 48 h) suppresses growth of Gram-positive Bacillus subtilis, Staphylococcus epidermidis, and Micrococcus luteus at an MIC of 64 μg/mL, and is inactive against the Gram-negative bacteria tested[2].
Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).
Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).
