| Field | Specification |
|---|---|
| CAS no. | |
| Applications | |
| Source | Microbial — Stenotrophomonas sp. Strain SB-K88 |
| Molecular weight | |
| Molecular formula | C29H38N2O6 |
| SMILES | |
| Storage | |
| Shipping | |
| Catalog no. (Mfr.) | |
| Main SKU |
Compound Overview
Xanthobaccin A is a potent antibiotic that can be isolated from the culture fluid of Stenotrophomonas sp. strain SB-K88. It is active against fungi and Gram-positive bacteria, induces zoospore immobilization and lysis, and inhibits mycelial growth, and it can be used in research on beet damping-off disease and bacterial and fungal infection[1][2][3][4]. It has the molecular formula C29H38N2O6 and a molecular weight of 510.62 g/mol.
Physical & Chemical Properties
| CAS Number | 227596-81-8 |
|---|---|
| Molecular Formula | C29H38N2O6 |
| Molecular Weight | 510.62 g/mol |
| Structure Classification | Antibiotics Disease Research Antifungal Antibiotics Beta-lactam Antibiotics Antibiotics Plant agriculture research |
| SMILES | O=C1[C@@]2([H])[C@@]([C@H]3C)([H])[C@](C[C@@H]3CC)([H])C[C@]2([H])[C@](C/C=C\C(NCC[C@H]4O)=O)([H])[C@@](/C=C/C(C(C5=O)=C([C@@]4([H])N5)O)=O)([H])C1 |
| Signaling Pathway | Anti-infection |
| Initial Source | Microbial — Stenotrophomonas sp. Strain SB-K88 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature in continental US; may vary elsewhere. |
Literature Cited
Sources cited in this description and in the In Vitro & In Vivo Data tab. Peer-reviewed publications that used this product are listed under References.
Safety
For Research Use Only. Not for use in diagnostic or therapeutic procedures, and not for human or veterinary use. Handle in accordance with your institution's chemical hygiene plan.
In Vitro
Motility of Aphanomyces cochlioides zoospores is potently inhibited, and lysis is induced, by Xanthobaccin A (0.001-10 μg/mL; 1-4 h) in a dose- and time-dependent manner, with an MIC of 0.01 μg/mL[1]. Mycelial growth is inhibited by Xanthobaccin A, which also induces abnormal morphological changes in Aphanomyces cochlioides hyphae[1]. Xanthobaccin A (0.1 μg/mL; 30 min) causes structural damage to Aphanomyces cochlioides zoospores and their lysis within 30 min[1]. The growth of several fungal plant pathogens (Phytophthora vignae f. sp. adzukicola, Gaeumannomyces graminis var. tritici, as well as Aphanomyces cochlioides and Pythium ultimum) is potently inhibited by Xanthobaccin A (20 μg per disk; 2-7 days)[2]. With a MIC of 1 μg/mL, Xanthobaccin A (1 μg/mL) inhibits growth of Pythium ultimum[3]. Growth of Bacillus subtilis is inhibited by Xanthobaccin A (20 μg; 24 h), with an MIC of 10 μg/mL[4]. As a ferric iron (Fe3+) metallophore, Xanthobaccin A is capable of chelating ferric iron ions[4].
Data provided by the manufacturer. Numbered citations refer to the Literature Cited list in the product description.
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