| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | Mirin |
| Cas No. | |
| Molecular Weight | |
| Product Type | |
| Signaling Pathway | |
| SMILES | |
| Target |
Compound Overview
(Z)-Mirin (CAS 1198097-97-0) is a research-grade small molecule supplied by TargetMol.
Alternative names: Mirin
Physical Properties
| CAS Number | 1198097-97-0 |
|---|---|
| Molecular Formula | C10H8N2O2S |
| Molecular Weight | 220.25 g/mol |
| SMILES | C(=C/1SC(N)=NC1=O)C2=CC=C(O)C=C2 |
| Form | Solid |
| Shipping | Room Temperature (RT) |
Biological Activity
(Z)-Mirin is a potent Mre11Rad50Nbs1 (MRN) complex inhibitor, and inhibits Mre11-associated exonuclease activity.
Target(s): ATM/ATR
Signaling pathway(s): PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair
Safety & Regulatory
For Research Use Only (RUO). Not for therapeutic, diagnostic, or clinical use. Wear appropriate PPE and consult the Safety Data Sheet (SDS) prior to handling.
Centrifuge the closed vial at 3000 rpm for 1–2 minutes to consolidate the powder at the bottom. For electrostatically charged powders, briefly warm the vial to room temperature and allow it to equilibrate before opening. Then add the appropriate solvent directly onto the powder and vortex before sonicating. Avoid tapping the vial vigorously, as this can generate fine powder aerosol.
sonication can accelerate dissolution. If the compound is not dissolving, sonication is recommended. If you don't have an ultrasound machine, a lower solvent concentration or using less powder are recommended.
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