| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | ZVAD-FMK, Z-VAD-FMK, Caspase Inhibitor I, Z-VAD (OMe)-FMK, Z-VAD(OMe)-FMK, Ac-ZVAD-FMK, benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone, carbobenzoxyvalyl-alanyl-aspartyl fluoromethyl ketone, FK 009, FK-009, FK009, Z-VAD.FMK, Z-Val-Ala-Asp-fluoromethylketone, ZVAD-fluoromethylketone, methyl (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-4-oxopentanoate |
| Cas No. | |
| Form | Lyophilized solid or wax |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | May be dissolved in DMSO (10 mg/ml) |
| Source | Synthetic |
| Storage |
Z-VAD-FMK is a broad-spectrum, irreversible pan-caspase inhibitor that blocks apoptosis by inhibiting caspase activation. In neuroscience, it is used to investigate the role of programmed cell death in neurodegenerative diseases, traumatic brain injury, and ischemic stroke. By preventing caspase-mediated neuronal apoptosis, Z-VAD-FMK helps delineate the molecular pathways involved in cell death and survival. It is also employed to study neuroinflammation and glial responses, making it a critical tool for exploring therapeutic interventions aimed at preserving neuronal integrity.
Details:
This product does not require a Material Safety Data Sheet under the Occupational Safety and Health Administration standard entitled "Hazard Communication" 29 CFR 1910.1200 for the United States.
The product does not meet the criteria of W.H.M.I.S. classification as a controlled product. As a result, a W.H.M.I.S. Material Safety Data Sheet is not required (in Canada) for this product.
Z-VAD-FMK (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-557)
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