Zebrafish Psmc2 Antibody / 26S proteasome regulatory subunit 7

SKU:BHA17136484
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NSJ Bioreagents
NSJ Bioreagents
Details Products
Overview
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Anti-PSMC2 antibody from Rabbit, polyclonal (rabbit origin), Rabbit Ig. Recommended for workflows such as Western blot (WB), IHC-P. Reactivity: Zebrafish. Supplied as antigen affinity purified format.
Target PSMC2
Host Rabbit
Reactivity Zebrafish
Application WB, IHC-P
Options selector
Catalog no. Formulation Size
RZ1289 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water; Size: 100 ug
  • Lead time: typically ships in ~2-3 business days; timing may vary by selected option.
  • Storage: After reconstitution, the Zebrafish Psmc2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • Shipping: cold-chain shipment (typically with ice packs).
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No RZ1289
Clonality
  • Polyclonal (rabbit origin)
Host Rabbit
Immunogen E. coli-derived zebrafish Psmc2 recombinant protein (amino acids K34-N433) was used as the immunogen for the Zebrafish Psmc2 antibody.
Isotype
  • Rabbit Ig
Product Type
  • Antibodies
  • Primary Antibodies
Purity Antigen affinity chromatography
Reactivity
  • Zebrafish
Storage After reconstitution, the Zebrafish Psmc2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target PSMC2
UniProt # Q7T3B1

Overview

Zebrafish Psmc2 Antibody / 26S proteasome regulatory subunit 7 is a anti-PSMC2 Rabbit antibody Polyclonal (rabbit origin) supplied in Antigen affinity purified format. Recommended for workflows such as Western blot (WB), IHC-P with listed reactivity in Zebrafish. Reported localization: Cytoplasm.

Key elements and design rationale

  • Target: PSMC2
  • Antibody details: Rabbit, Polyclonal (rabbit origin), isotype Rabbit Ig
  • Format: Antigen affinity purified
  • Applications (as listed): WB, IHC-P

Biological background

26S protease regulatory subunit 7, also known as 26S proteasome AAA-ATPase subunit Rpt1, is an enzyme that in humans is encoded by the PSMC2 gene. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit has been shown to interact with several of the basal transcription factors so, in addition to participation in proteasome functions, this subunit may participate in the regulation of transcription. This subunit may also compete with PSMC3 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Research relevance and current trends

  • Connecting protein-level changes to phenotype using orthogonal readouts (genetic perturbation, transcriptomics, imaging).
  • Considering isoforms and post-translational regulation when interpreting protein-level changes.
  • Comparing results across species and model systems with matched controls.

Common research applications

  • Western blotting: compare relative abundance and activation-state changes across conditions.
  • Immunohistochemistry: map target signal in tissue context and compare regions/phenotypes.

Interpret changes in signal alongside appropriate controls and, when relevant, in parallel with total-protein or pathway readouts.

Notes for experimental interpretation

  • Signal can reflect expression level, isoform composition, and post-translational state; interpret results in the context of your model system and stimuli.
  • Species differences and sample matrices can influence epitope recognition; prioritize matched controls and orthogonal confirmation when feasible.

Antibody notes: Polyclonal antibodies recognize multiple epitopes, which can broaden the epitope footprint and may increase sensitivity in some contexts.

Customization & Add-ons: Can’t find the antibody you need—or require a custom format for your assay? We can help you source the best match or support custom antibody solutions for diverse research needs, including species and isotype selection, conjugations and labeling (e.g., HRP/AP, biotin, fluorophores), purification grade options (Protein A/G, affinity purified), formulation preferences (buffer selection, carrier-free, glycerol-free), custom concentrations and aliquoting, low-endotoxin options for cell-based work, and application-focused QC/validation support (project dependent). Click Talk to a Scientist to submit a request, email us at support@biohippo.com, or explore our Research Services for additional support—our team will follow up with feasibility details and next steps.

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Experience the power of Celltrypse™, c-LEcta's innovative enzyme solution for gentle and efficient cell dissociation. Request your free sample and discover a superior alternative for your cell culture workflows.

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