Zerumbone

SKU:BHB11900087
Suppliers
StressMarq Biosciences Inc.
StressMarq Biosciences Inc.
Details Products
Overview
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Zerumbone is a research-grade small-molecule inhibitor of NF-κB kinase for Cancer and Apoptosis studies. Supplied as a white to off-white solid with >98% purity (CAS 471-05-6, MW 218.3) soluble in DMSO; store at -20°C. For research use only.
Cas No. 471-05-6
Molecular Formula C15H22O
Purity >98%
Application Notes NF-κB kinase inhibitor
Options selector
Catalog no. Size
SIH-265-10MG 10 mg
SIH-265-50MG 50 mg
Available Options

Select the variant that best fits your experiment. Availability and lead time may vary by option.

  • Options: Size (2) — 10 mg, 50 mg.
  • Lead time: options listed as “in stock at manufacturer” typically ship in 2-3 business days; other statuses may take longer.
  • Storage: -20ºC
  • Shipping: ships at ambient temperature.
  • Upon receipt: store at the recommended temperature as soon as possible.
  • Sales terms and conditions: Please review prior to ordering.
Field Specification
Mfr No SIH-265
Activity
  • Inhibitor
Alternative Names (2E,6E,10E)-2,6,9,9-Tetramethyl-2,6,10-cycloundecatrien-1-one
Cas No. 471-05-6
Form White to off-white solid
Molecular Weight 218.3
Product Type
  • Biochemicals
  • Small Molecules
Purity >98%
Shipping Shipped Ambient
SMILES C/C/1=C\CC(/C=C/C(=O)/C(=C/CC1)/C)(C)C
Solubility Soluble in DMSO (≥10 mg/ml)
Source Synthetic
Storage -20ºC

Zerumbone is a natural sesquiterpene ketone isolated from Zingiber species, known for its anti-inflammatory and anticancer properties. In neuroscience, zerumbone has been investigated for its ability to potentiate TRAIL-induced apoptosis via upregulation of death receptors DR4 and DR5. Its selective cytotoxicity toward abnormal cells and ability to modulate apoptotic pathways make it a compound of interest in neuro-oncology and neurodegenerative disease research.

Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin.

Safety Phrases:

  • S22 - Do not breathe dust
  • S24/25 - Avoid contact with skin and eyes
  • S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Zerumbone (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-265)

Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.

  • Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
  • Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
  • Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
  • QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
  • Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity

To quote quickly, tell us: compound name + CAS/structure (SMILES or mol file), intended assay context, solvent preference, salt/stereochemistry requirements, purity/QC level, and the amount (mg–g).

Can’t find the compound you’re looking for?
Send the CAS or structure and your specs. We can help source it, suggest close equivalents, or discuss custom synthesis with the right QC documentation (RUO).

1. Leu J.L., et al. (2009) Mol Cell. 36:15.

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