| Field | Specification |
|---|---|
| Mfr No | |
| Activity | |
| Alternative Names | Benzyl [(2S)-4-chloro-3-oxo-1-phenyl-2-butanyl]carbamate; N-Benzyloxycarbonyl-Lphenylalaninylchloromethyl ketone; ZPCK |
| Cas No. | |
| Form | White Solid |
| Molecular Weight | |
| Product Type | |
| Purity | |
| Shipping | |
| SMILES | |
| Solubility | Soluble in 50 mg/ml DMSO oir 15 mg/ml warm Ethanol |
| Source | Synthetic |
| Storage |
ZPCK (SL-01) is a small molecule that inhibits the p53-MDM2 interaction at micromolar concentrations (20 µM). It has also been shown to inhibit bovine chymotrypsin A-y, indicating potential protease inhibitory activity. By disrupting the p53-MDM2 axis, ZPCK may stabilize p53 and promote its transcriptional activity, which is relevant in both cancer biology and neurodegenerative disease models. In the nervous system, p53 plays a dual role in regulating apoptosis and neuronal survival, making ZPCK a candidate for probing p53-mediated pathways in neurodegeneration.
Classification: Caution – Substance not yet fully tested.
Safety Phrases:
- S22 - Do not breathe dust
- S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
- S24/25- Avoid contact with skin and eyes
ZPCK (SL-01) (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SIH-343)
Need this compound in a format that drops straight into your assay? We can tailor formulation, chemistry, and documentation so your results stay consistent across runs and re-orders.
- Format options: solid or pre-dissolved solution (choose solvent), target concentration, aliquots, light/moisture-protected packaging
- Chemistry options: free base/acid vs salt forms, hydrate/solvate preference, stereoisomer control (single enantiomer or racemate), close analogs
- Add-on labels & handles: D/¹³C/¹⁵N isotopes (LC-MS/internal standards), azide/alkyne or other functional handles for conjugation
- QC & documentation: standard COA or enhanced analytical pack (HPLC/LC-MS/NMR), chiral purity, residual solvents, water content (KF), method-specific specs
- Scale & continuity: mg to gram scale, bulk pricing, lot reservation, repeat-order continuity
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