Recombinant membrane proteins reconstituted in nanodiscs — a native-like lipid bilayer environment for functional, cryo-EM and binding studies.
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Target: GPR19 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR78 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR15 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR83 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR6 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR21 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR62 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GP142 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR61 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR27 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR3 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR52 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GRM3 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR85 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR37 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR35 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR31 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR18 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR42 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR34 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GP183 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GP153 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GP171 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR12 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR45 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GP150 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GP160 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR4 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GP179 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPER1 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GP162 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GP182 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPR161 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Target: GPBAR1 | Recombinant Protein | Functional Assay (In Vitro) ELISA |
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Target: GPC5B | Recombinant Protein | Functional Assay (In Vitro) ELISA |
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Target: GP152 | Transmembrane Protein | Functional Assay (In Vitro) ELISA |
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Nanodiscs wrap a single membrane protein in a small disc of native lipid bilayer held by two membrane scaffold proteins, keeping the target water-soluble while preserving a near-native lipid environment. This collection lists recombinant membrane proteins supplied pre-reconstituted in nanodiscs.
Every product here is supplied in a nanodisc. Here is how that choice compares with the two other formats we stock, so you can confirm it fits your experiment.
| Consideration | Nanodisc | Detergent micelle | VLP |
|---|---|---|---|
| Lipid environment | Native lipid bilayer disc | Detergent shell (lipids removed) | Native membrane on a capsid |
| Native function preserved | High | Variable — often reduced for GPCRs | High (keeps oligomeric state) |
| Best structural method | Single-particle cryo-EM | X-ray crystallography / LCP | Not for high-resolution structure |
| Display / valency | Monomeric, defined stoichiometry | Monomeric | Multivalent — many copies per particle |
| Typical particle | ~9–13 nm disc | Protein–detergent micelle | ~100 nm engineered capsid |
| Best for | Function + cryo-EM, SPR / BLI binding | Broad selection, high-res X-ray, cost | Immunization, antibody discovery, vaccines |
| Watch-outs | Disc size caps very large complexes | May alter GPCR conformation / stability | Less suited to atomic-resolution structure |
How to read this: if you need the protein to behave as it does in a cell — ligand binding, channel gating, GPCR pharmacology — and you are heading toward cryo-EM, the nanodisc format is usually the right starting point. Choose detergent when you need the broadest selection or high-resolution X-ray, and VLPs when multivalent, native-oligomeric display matters (for example, raising antibodies).
Showing current best-selling items in this collection — updates automatically.
