Heat Shock Proteins & Chaperones

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1075 products
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Chemical structure of Cyclosporine (SIH-201), a Inhibits mitochondrial permeability pore opening. CAS #: 59865-13-3. Molecular Formula: C62H111N11O12 . Molecular Weight: 1202.63 g/mol.
Cyclosporine
— Functional Assay (In Vitro) —
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Chemical structure of 17-DMAG (SIH-114), a Hsp90 inhibitor. CAS #: 467214-20-6. Molecular Formula: C32H48N4O8. Molecular Weight: 616.8 g/mol.
17-DMAG
— Functional Assay (In Vitro) —
From $128.75
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Chemical structure of Actinomycin D (SIH-245), a Transcription inhibitor. CAS #: 50-76-0. Molecular Formula: C62H86N12O16. Molecular Weight: 1255.43 g/mol.
Actinomycin D
— Functional Assay (In Vitro) —
From $106.09
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Chemical structure of Cytochalasin D (SIH-241), a Disrupts actin filaments. CAS #: 22144-77-0. Molecular Formula: C30H37NO6. Molecular Weight: 507.63 g/mol.
Cytochalasin D
— Functional Assay (In Vitro) —
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Chemical structure of Valinomycin (SIH-230), a Induces loss of mitochondrial membrane potential. CAS #: 2001-95-8. Molecular Formula: C54H90N6O18. Molecular Weight: 1111.32 g/mol.
Valinomycin
— Functional Assay (In Vitro) —
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Chemical structure of R(-)-Gossypol (SIH-223), a Bcl-2 inhibitor. CAS #: 303-45-7. Molecular Formula: C30H30O8. Molecular Weight: 518.56 g/mol.
R(-)-Gossypol
— Functional Assay (In Vitro) —
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Chemical structure of 17-AAG (SIH-100), a Hsp90 inhibitor. CAS #: 75747-14-7. Molecular Formula: C31H43N3O8. Molecular Weight: 585.7 g/mol.
17-AAG
— Functional Assay (In Vitro) —
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Chemical structure of FCCP (SIH-222), a Inhibits mitochondrial oxidative phosphorylation. CAS #: 370-86-5. Molecular Formula: C10H5F3N4O. Molecular Weight: 254.17 g/mol.
FCCP
— Functional Assay (In Vitro) —
From $73.13
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Hsp70 TKD Peptide: FITC
— Functional Assay (In Vitro) —
$310.03
$310.03
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Hsp70 TKD Peptide
— Functional Assay (In Vitro) —
$260.59
$260.59
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Chemical structure of Betulinic Acid (SIH-221), a Induces mitochondrial permeability pore opening. CAS #: 472-15-1. Molecular Formula: C30H48O3 . Molecular Weight: 456.7 g/mol.
Betulinic Acid
— Functional Assay (In Vitro) —
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Chemical structure of VU0467154 (SIH-184), a M4 Receptor Agonist. CAS #: 1451993-15-9. Molecular Formula: C17H15F3N4O3S2. Molecular Weight: 444.45 g/mol.
VU0467154
— Functional Assay (In Vitro) —
$242.05
$242.05
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Chemical structure of TEMPO (SIH-155), a Stabilized free radical. CAS #: 2564-83-2. Molecular Formula: C9H18NO . Molecular Weight: 156.25 g/mol.
TEMPO
— Functional Assay (In Vitro) —
$27.81
$27.81
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Chemical structure of Herbimycin A (SIH-116), a Hsp90 inhibitor. CAS #: 70563-58-5. Molecular Formula: C30H42N2O9. Molecular Weight: 574.3 g/mol.
Herbimycin A
— Functional Assay (In Vitro) —
From $175.10
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Chemical structure of Sphingosine (SIH-202), a Protein Kinase C inhibitor. CAS #: 123-78-4. Molecular Formula: C18H37NO2. Molecular Weight: 299.49 g/mol.
Sphingosine
— Functional Assay (In Vitro) —
From $108.15
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Chemical structure of CCT196969 (SIH-185), a RAF Inhibitor. CAS #: 1163719-56-9. Molecular Formula: C27H24FN7O3. Molecular Weight: 513.53 g/mol.
CCT196969
— Functional Assay (In Vitro) —
$415.09
$415.09
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Chemical structure and design of FCR1 (SIH-180), showing FRET processes in oxidised form. Inset: photographs of cuvettes of FCR1 in oxidised and reduced forms under 365 nm excitation. Images used with permission from Kaur A, Haghighatbin MA, Hogan CF, New EJ. Chem Commun (Camb). 2015 Jun 16;51(52):10510-3.
FCR1
— Functional Assay (In Vitro) —
$501.61
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Chemical structure of TPCK (SIH-207), a Serine protease inhibitor. CAS #: 402-71-1. Molecular Formula: C17H18CI3O3S. Molecular Weight: 351.85 g/mol.
TPCK
— Functional Assay (In Vitro) —
$119.48
$119.48
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Chemical structure of Geldanamycin- FITC (SIH-113), a Hsp90 inhibitor. Molecular Formula: C55H63N5O13S. Molecular Weight: 560.6 g/mol.
Geldanamycin: FITC
— Functional Assay (In Vitro) —
$237.93
$237.93
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Chemical structure of 17-GMB-APA-GA (SIH-115), a Hsp90 inhibitor. CAS #: N/A. Molecular Formula: C39H53N5O11. Molecular Weight: 767.9 g/mol.
17-GMB-APA-GA
— Functional Assay (In Vitro) —
$237.93
$237.93
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Chemical structure of Geldanamycin- Biotin (SIH-112), a Hsp90 inhibitor. CAS #: 30562-34-6. Molecular Formula: C55H87N7O17S. Molecular Weight: 560.6 g/mol.
Geldanamycin: Biotin
— Functional Assay (In Vitro) —
$218.36
$218.36
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Chemical structure of YM-01 (SIH-121), a Hsp70 Inhibitor. CAS #: 409086-68-6. Molecular Formula: C20H20ClN3OS2. Molecular Weight: 417.97 g/mol.
YM-01
— Functional Assay (In Vitro) —
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Chemical structure of Geldanamycin (SIH-111), a Hsp90 inhibitor. CAS #: 30562-34-6. Molecular Formula: C29H40N2O9. Molecular Weight: 560.6 g/mol.
Geldanamycin
— Functional Assay (In Vitro) —
From $76.22
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Rabbit Anti-HSP70 Antibody (Acetyl Lys77) used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Embryonic kidney cells (HEK293) cultured overnight with 50 µM H2O2 (SPC-743)
HSP70 Antibody (Acetyl Lys77)
Target: HSP70
 HSP70 Western Blot, ELISA, Immunofluorescence, Immunohistochemistry Human, Mouse, Rat
From $429.51
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Rabbit Anti-HSP60 Antibody used in Immunohistochemistry (IHC) on Liver (SPC-185)
HSP60 (P. falciparum) Antibody
Target: HSP60 (P. falciparum)
 HSP60 (P. falciparum) Western Blot, Immunofluorescence, Immunohistochemistry P. falciparum, Bacteria, Human
From $347.11
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Chicken Anti-Hsp70 Antibody used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Heat Shocked Cervical cancer cell line (HeLa) (SPC-178)
HSP70 Antibody
Target: HSP70
 HSP70 Western Blot, Immunofluorescence, ELISA Human, Mouse, Rat
From $344.02
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Rabbit Anti-HSP70 Antibody used in Western blot (WB) on Lysates (SPC-186)
HSP70 (P. falciparum) Antibody
Target: HSP70 (P. falciparum)
 HSP70 (P. falciparum) Western Blot, Immunofluorescence P. falciparum, Viral/Pathogen
From $347.11
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Rabbit Anti-Hsp70 Antibody used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human Heat Shocked HeLa Cells (SPC-103)
HSP70 Antibody
Target: HSP70
 HSP70 Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation, ELISA, Flow Cytometry Human, Mouse, Rat, Beluga, Bovine, Dog, Fish, Carp, Guinea Pig, Hamster, Monkey, Pig, Sheep, Coral, Plant, Shark, L. amazonensis, Viral/Pathogen
From $344.02
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Rabbit Anti-HSP90 Antibody used in Western blot (WB) on Lysates (SPC-187)
HSP90 (P. falciparum) Antibody
Target: HSP90 (P. falciparum)
 HSP90 (P. falciparum) Western Blot, Immunofluorescence, Immunoprecipitation P. falciparum, Viral/Pathogen
From $347.11
From $347.11
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Rabbit Anti-Hsp60 Antibody used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human Heat Shocked HeLa Cells (SPC-105)
HSP60 Antibody
Target: HSP60
 HSP60 Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation, ELISA Human, Mouse, Rat, Bovine, Dog, Chicken, Rabbit, Hamster
From $315.18
From $315.18
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Rabbit Anti-Hsp27 Antibody used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human Heat Shocked HeLa Cells (SPC-106)
HSP27 Antibody
Target: HSP27
 HSP27 Western Blot, Immunofluorescence, Flow Cytometry, Immunohistochemistry Human, Mouse, Shark, Dog
From $289.43
From $289.43
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Rabbit Anti-Hsp90 Antibody used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human Heat Shocked HeLa Cells (SPC-104)
HSP90 Antibody
Target: HSP90
 HSP90 Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation, ELISA Human, Mouse, Rat
From $291.49
From $291.49
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HSP70 Antibody
Target: HSP70
 HSP70 Western Blot, Immunofluorescence, ELISA Drosophila
From $330.63
From $330.63
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Mouse Anti-HSP70 Antibody [3A3] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human Cervical cancer cell line (HeLa) (SMC-164)
HSP70 Antibody
Target: HSP70
 HSP70 Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation, Calcium Imaging Human, Mouse, Rat, Amphibians, Chicken, Fish, Yeast, Drosophila, Bacteria, Brine Shrimp
From $326.51
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Mouse Anti-HSP70 Antibody: FITC [1H11] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on non-permeabilized Human HCT116 cells (SMC-249)
RECOMBINANT HSP70 Antibody
Target: HSP70
 HSP70 Western Blot, Immunofluorescence, Flow Cytometry Human, Mouse, Rat, Bovine, Pig
From $413.03
From $413.03
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Mouse Anti-HSP70 Antibody [5A5] used in Immunocytochemistry/Immunofluorescence (ICC/IF) on Human Cervical cancer cell line (HeLa) (SMC-162)
HSP70 Antibody
Target: HSP70
 HSP70 Western Blot, Immunohistochemistry, Immunofluorescence, Immunoprecipitation, Calcium Imaging Human, Mouse, Rat, Amphibians, Chicken, Fish, Yeast, Drosophila
From $326.51
From $326.51
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About Heat Shock Proteins & Chaperones

Antibodies, ELISA kits, and recombinant proteins for studying molecular chaperones, the heat shock response, and protein quality control. The category covers the major chaperone families — HSP90 (HSP90AA1, HSP90AB1, GRP94/HSP90B1, TRAP1/HSP75), HSP70 (HSPA1A, HSPA8, HSPA9/mortalin, GRP78/HSPA5), the small heat shock proteins (HSP27/HSPB1 and HSPB2–HSPB8), the chaperonins (HSP60/HSPD1 and HSP10), and the DNAJ/HSP40 co-chaperones — together with the HSP90 co-chaperone machinery (CDC37, HOP/STIP1, p23/PTGES3, AHA1/AHSA1) and the transcription factor HSF1 that drives the heat shock response. Use it to source validated reagents for proteostasis, chaperone-inhibitor, and cellular-stress research across human and preclinical species.

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